Due to scheduled maintenance work, this service will not be available from Tuesday August 23rd 06:00 pm until Wednesday August 24th 08:00 am
CEST. Apologies for the inconvenience.
Cellosaurus VCaP-R (CVCL_C0QQ)
[Text version]
| Cell line name |
VCaP-R
|
|---|
| Accession |
CVCL_C0QQ
|
|---|
| Resource Identification Initiative |
To cite this cell line use: VCaP-R (RRID:CVCL_C0QQ) |
|---|
| Comments |
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
|
|---|
| Sequence variations |
- Gene fusion; HGNC; 3446; ERG + HGNC; 11876; TMPRSS2; Name(s)=TMPRSS2-ERG (from parent cell line).
- Mutation; HGNC; 7127; MLH1; Simple; p.Ile219Val (c.655A>G); ClinVar=VCV000036557; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
|
|---|
| Disease |
Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Bone; vertebra.
|
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
|---|
| Hierarchy |
Parent: CVCL_2235 (VCaP)
|
|---|
| Sex of cell |
Male
|
|---|
| Age at sampling |
59Y
|
|---|
| Category |
Cancer cell line
|
|---|
| Publications | PubMed=30244336; DOI=10.1007/s00345-018-2501-6
Samli H., Samli M., Vatansever B., Ardicli S., Aztopal N., Dincel D., Sahin A., Balci F.
Paclitaxel resistance and the role of miRNAs in prostate cancer cell lines.
World J. Urol. 37:1117-1126(2019) |
|---|
| Entry history |
|---|
| Entry creation | 23-Jun-2022 |
|---|
| Last entry update | 23-Jun-2022 |
|---|
| Version number | 1 |
|---|