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Cellosaurus SSK41 (CVCL_C123)

[Text version]
Cell line name SSK41
Synonyms SSK-41
Accession CVCL_C123
Resource Identification Initiative To cite this cell line use: SSK41 (RRID:CVCL_C123)
Comments Characteristics: Expresses surface IgM but can spontaneously switch to the production of IgG1 or IgG3.
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Miscellaneous: Originally assigned to be from a follicular lymphoma.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Disease Splenic marginal zone lymphoma (NCIt: C4663)
Splenic marginal zone lymphoma (ORDO: Orphanet_86854)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VC39 (SSKWB)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2518730; DOI=10.1093/intimm/1.6.631
Sideras P., Mizuta T.-R., Kanamori H., Suzuki N., Okamoto M., Kuze K., Ohno H., Doi S., Fukuhara S., Hassan M.S., Hammarstrom L., Smith E., Shimizu A., Honjo T.
Production of sterile transcripts of C gamma genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells.
Int. Immunol. 1:631-642(1989)

PubMed=1712020; DOI=10.1016/S0021-9258(18)98929-5
Mizuta T.-R., Suzuki N., Shimizu A., Honjo T.
Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells.
J. Biol. Chem. 266:12514-12521(1991)

PubMed=7849311; DOI=10.1182/blood.V85.4.893.bloodjournal854893
Stranks G., Height S.E., Mitchell P., Jadayel D.M., Yuille M.A.R., De Lord C., Clutterbuck R.D., Treleaven J.G., Powles R.L., Nacheva E., Oscier D.G., Karpas A., Lenoir G.M., Smith S.D., Millar J.L., Catovsky D., Dyer M.J.S.
Deletions and rearrangement of CDKN2 in lymphoid malignancy.
Blood 85:893-901(1995)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Mestre-Escorihuela C., Rubio-Moscardo F., Richter J.A., Siebert R., Climent J., Fresquet V., Beltran E., Agirre X., Marugan I., Marin M., Rosenwald A., Sugimoto K.-j., Wheat L.M., Karran E.L., Garcia J.F., Sanchez-Verde L., Prosper F., Staudt L.M., Pinkel D., Dyer M.J.S., Martinez-Climent J.A.
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C123
Encyclopedic resources Wikidata; Q54955698
Gene expression databases GEO; GSM115988
GEO; GSM866166
GEO; GSM1035347
GEO; GSM1035348
Polymorphism and mutation databases Cosmic; 1291154
Cosmic; 2297033
Cosmic; 2590021
Progenetix; CVCL_C123
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number15