Home  |  Contact

Cellosaurus SKH1 [Human leukemia] (CVCL_C124)

Cell line name SKH1 [Human leukemia]
Synonyms SKH-1
Accession CVCL_C124
Resource Identification Initiative To cite this cell line use: SKH1 [Human leukemia] (RRID:CVCL_C124)
Comments Population: Japanese.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=8313895).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8313895; DOI=10.1002/j.1460-2075.1994.tb06288.x
Mitani K., Ogawa S., Tanaka T., Miyoshi H., Kurokawa M., Mano H., Yazaki Y., Ohki M., Hirai H.
Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.
EMBO J. 13:504-510(1994)

PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x
Hosoya N., Hangaishi A., Ogawa S., Miyagawa K., Mitani K., Yazaki Y., Hirai H.
Frameshift mutations of the hMSH6 gene in human leukemia cell lines.
Jpn. J. Cancer Res. 89:33-39(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=15156182; DOI=10.1038/sj.onc.1207777
Mitani K.
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
Oncogene 23:4263-4269(2004)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

Cross-references
Encyclopedic resources Wikidata; Q54954739
Polymorphism and mutation databases Cosmic; 919117
Cosmic; 947370
Cosmic; 1012118
Entry history
Entry creation06-Jun-2012
Last entry update21-Mar-2023
Version number12