ID   HS181
AC   CVCL_C229
SY   KIe001-A
DR   GEO; GSM569193
DR   GEO; GSM569194
DR   GEO; GSM1293456
DR   GEO; GSM1293457
DR   GEO; GSM1293458
DR   GEO; GSM1293459
DR   hPSCreg; KIe001-A
DR   ISCR; 522
DR   SKIP; SKIP001792
DR   Wikidata; Q54896297
RX   PubMed=12832363;
RX   PubMed=17572666;
RX   PubMed=18930318;
RX   PubMed=20198446;
RX   PubMed=20641038;
RX   PubMed=20736931;
RX   PubMed=21217828;
RX   PubMed=24463987;
RX   PubMed=32339905;
CC   From: Karolinska Institutet; Stockholm; Sweden.
CC   Registration: Swiss research registry; BAG-hES-IMP-0009.
CC   Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC03-09.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 15
//
RX   PubMed=12832363; DOI=10.1093/humrep/deg290;
RA   Hovatta O., Mikkola M., Gertow K., Stromberg A.-M., Inzunza J.,
RA   Hreinsson J., Rozell B., Blennow E., Andang M., Ahrlund-Richter L.;
RT   "A culture system using human foreskin fibroblasts as feeder cells
RT   allows production of human embryonic stem cells.";
RL   Hum. Reprod. 18:1404-1409(2003).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J.,
RA   Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S.,
RA   Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=18930318; DOI=10.1016/j.leukres.2008.08.028;
RA   Catalina P., Bueno C., Montes R., Nieto A., Ligero G., Sanchez L.,
RA   Jara M., Rasillo A., Orfao A., Cigudosa J.C., Hovatta O., Greaves M.F.,
RA   Menendez P.;
RT   "Genetic stability of human embryonic stem cells: a first-step toward
RT   the development of potential hESC-based systems for modeling childhood
RT   leukemia.";
RL   Leuk. Res. 33:980-990(2009).
//
RX   PubMed=20198446; DOI=10.1007/s11626-010-9308-0;
RA   Strom S., Holm F., Bergstrom R., Stromberg A.-M., Hovatta O.;
RT   "Derivation of 30 human embryonic stem cell lines -- improving the
RT   quality.";
RL   In Vitro Cell. Dev. Biol. Anim. 46:337-344(2010).
//
RX   PubMed=20641038; DOI=10.1002/stem.471;
RA   Gutierrez-Aranda I., Ramos-Mejia V., Bueno C., Munoz-Lopez M.,
RA   Real P.J., Macia A., Sanchez L., Ligero G., Garcia-Parez J.L.,
RA   Menendez P.;
RT   "Human induced pluripotent stem cells develop teratoma more
RT   efficiently and faster than human embryonic stem cells regardless the
RT   site of injection.";
RL   Stem Cells 28:1568-1570(2010).
//
RX   PubMed=20736931; DOI=10.1038/mt.2010.179;
RA   Ramos-Mejia V., Melen G.J., Sanchez L., Gutierrez-Aranda I.,
RA   Ligero G., Cortes J.L., Real P.J., Bueno C., Menendez P.;
RT   "Nodal/activin signaling predicts human pluripotent stem cell lines
RT   prone to differentiate toward the hematopoietic lineage.";
RL   Mol. Ther. 18:2173-2181(2010).
//
RX   PubMed=21217828; DOI=10.1371/journal.pone.0015329;
RA   Strom S., Rodriguez-Wallberg K., Holm F., Bergstrom R., Eklund L.,
RA   Stromberg A.-M., Hovatta O.;
RT   "No relationship between embryo morphology and successful derivation
RT   of human embryonic stem cell lines.";
RL   PLoS ONE 5:E15329-E15329(2010).
//
RX   PubMed=24463987; DOI=10.1038/ncomms4195;
RA   Rodin S., Antonsson L., Niaudet C., Simonson O.E., Salmela E.,
RA   Hansson E.M., Domogatskaya A., Xiao Z.-J., Damdimopoulou P., Sheikhi M.,
RA   Inzunza J., Nilsson A.-S., Baker D.E.C., Kuiper R., Sun Y., Blennow E.,
RA   Nordenskjold M., Grinnemo K.-H., Kere J., Betsholtz C., Hovatta O.,
RA   Tryggvason K.;
RT   "Clonal culturing of human embryonic stem cells on
RT   laminin-521/E-cadherin matrix in defined and xeno-free environment.";
RL   Nat. Commun. 5:3195.1-3195.13(2014).
//
RX   PubMed=32339905; DOI=10.1016/j.scr.2020.101810;
RA   Main H., Hedenskog M., Acharya G., Hovatta O., Lanner F.;
RT   "Karolinska Institutet Human Embryonic Stem Cell Bank.";
RL   Stem Cell Res. 45:101810-101810(2020).
//