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Cellosaurus I 4 (CVCL_C379)

Cell line name I 4
Synonyms I4; Israel number 4; TE04; TE-04; TECHe002-A
Accession CVCL_C379
Resource Identification Initiative To cite this cell line use: I 4 (RRID:CVCL_C379)
Comments From: Technion - Israel Institute of Technology; Haifa; Israel.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0205.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
HLA typing Source: PubMed=16919167
Class I
HLA-AA*03:24
HLA-BB*35:02,38
HLA-CC*04,12
Class II
HLA-DQDQB1*01,06
HLA-DRDRB1*13,13
DRB3*01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=16919167; WiCell

Markers:
AmelogeninX
CSF1PO12
D5S81811,12
D7S82012,13
D13S31712,14 (PubMed=16919167)
12,14,15 (WiCell)
D16S53911,12
TH017,9
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Web pages https://stemcelldb.nih.gov/cellLineDetails.do?id=42
Publications

PubMed=16919167; DOI=10.1186/1741-7007-4-28
Josephson R., Sykes G.R., Liu Y., Ording C.J., Xu W.-N., Zeng X.-M., Shin S., Loring J.F., Maitra A., Rao M.S., Auerbach J.M.
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=23117585; DOI=10.1016/j.scr.2012.09.002
Mallon B.S., Chenoweth J.G., Johnson K.R., Hamilton R.S., Tesar P.J., Yavatkar A.S., Tyson L.J., Park K., Chen K.G., Fann Y.C., McKay R.D.G.
StemCellDB: the human pluripotent stem cell database at the National Institutes of Health.
Stem Cell Res. 10:57-66(2013)

PubMed=28445466; DOI=10.1038/nature22312
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line collections (Providers) WiCell; te04
Cell line databases/resources hPSCreg; TECHe002-A
ISCR; 122
NIHhESC; NIHhESC-13-0205
SKIP; SKIP001860
Encyclopedic resources Wikidata; Q54897063
Gene expression databases GEO; GSM856735
GEO; GSM862726
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number19