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Cellosaurus FM55p (CVCL_C591)

Cell line name FM55p
Synonyms FM55P; FM-55-P; FM 55P
Accession CVCL_C591
Resource Identification Initiative To cite this cell line use: FM55p (RRID:CVCL_C591)
Comments Derived from site: In situ; Skin; UBERON=UBERON_0002097.
HLA typing Source: PubMed=7656272
Class I
HLA-AA*01,02
HLA-BB*15,28
HLA-CC*03

Source: PubMed=15592718
Class I
HLA-AA*01:01,02:01
HLA-BB*08:01,15:01:01:01
HLA-CC*03:04,07:01:01
Class II
HLA-DPDPB1*04:01
HLA-DQDQB1*03:02,03:01:01
HLA-DRDRB1*04:02,04:01:01
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C592 (FM55p.R22.2)
Originate from same individual CVCL_C589 ! FM55M1
CVCL_C590 ! FM55M2
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ECACC=13012417; ESTDAB=ESTDAB-014

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135814
D5S81810,11
D7S8208,10
D13S31711
D16S53912,13
FGA24
TH015,7
TPOX9,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=7656272; DOI=10.1007/BF01527402
Kirkin A.F., Petersen T.R., Olsen A.C., Li L., thor Straten P., Zeuthen J.
Generation of human-melanoma-specific T lymphocyte clones defining novel cytolytic targets with panels of newly established melanoma cell lines.
Cancer Immunol. Immunother. 41:71-81(1995)

PubMed=8665567; DOI=10.1007/s002620050272
Kirkin A.F., thor Straten P., Zeuthen J.
Differential modulation by interferon gamma of the sensitivity of human melanoma cells to cytolytic T cell clones that recognize differentiation or progression antigens.
Cancer Immunol. Immunother. 42:203-212(1996)

PubMed=8968104
Bartkova J., Lukas J., Guldberg P., Alsner J., Kirkin A.F., Zeuthen J., Bartek J.
The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.
Cancer Res. 56:5475-5483(1996)

PubMed=9688544; DOI=10.1016/S0014-5793(98)00603-6
Dzhandzhugazyan K.N., Kirkin A.F., thor Straten P., Zeuthen J.
Ecto-ATP diphosphohydrolase/CD39 is overexpressed in differentiated human melanomas.
FEBS Lett. 430:227-230(1998)

PubMed=11225993; DOI=10.1007/s002620000154
Real L.M., Jimenez P., Kirkin A.F., Serrano A., Garcia A., Canton J., Zeuthen J., Garrido F., Ruiz-Cabello Osuna F.
Multiple mechanisms of immune evasion can coexist in melanoma tumor cell lines derived from the same patient.
Cancer Immunol. Immunother. 49:621-628(2001)

PubMed=15592718; DOI=10.1007/s00262-004-0561-5
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A., Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

Cross-references
Cell line collections (Providers) ECACC; 13012417
Cell line databases/resources ESTDAB; ESTDAB-014
Encyclopedic resources Wikidata; Q54835048
Polymorphism and mutation databases Cosmic; 808536
Cosmic; 972263
Cosmic; 1006223
Entry history
Entry creation22-Oct-2012
Last entry update02-May-2024
Version number16