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Cellosaurus UKRV-Mel-12b (CVCL_C660)

[Text version]
Cell line name UKRV-Mel-12b
Accession CVCL_C660
Resource Identification Initiative To cite this cell line use: UKRV-Mel-12b (RRID:CVCL_C660)
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; 11730; TERT; Simple; c.228_229CC>TT (-124/-125CC>TT); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C659 ! UKRV-Mel-12a
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB

Markers:
AmelogeninX
CSF1PO11,12
D3S135815,18
D5S81812
D7S8208,11
D13S3178,11
FGA22,25
TH017,9.3
TPOX8,9
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C660
ESTDAB; ESTDAB-224
Encyclopedic resources Wikidata; Q54990569
Polymorphism and mutation databases Cosmic; 1846698
Cosmic; 2686511
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number12