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Cellosaurus HT29-16E (CVCL_C763)

[Text version]

Cell line name HT29-16E
Synonyms HT29 16E; HT-29 16E; HT29-Cl.16E; HT29 clone 16E; Cl.16E
Accession CVCL_C763
Resource Identification Initiative To cite this cell line use: HT29-16E (RRID:CVCL_C763)
Comments Misspelling: C1.16E; Occasionally.
Sequence variations Mutation; HGNC; 583; APC; Simple; p.Glu853Ter (c.2557G>T); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0320 (HT-29)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
Publications

PubMed=6744312
Augeron C., Laboisse C.L.
Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.
Cancer Res. 44:3961-3969(1984)

PubMed=8801204; DOI=10.1136/gut.38.2.240
Jarry A., Vallette G., Branka J.E., Laboisse C.
Direct secretory effect of interleukin-1 via type I receptors in human colonic mucous epithelial cells (HT29-Cl.16E).
Gut 38:240-242(1996)

Cross-references
Other Wikidata; Q54896586
Entry history
Entry creation22-Oct-2012
Last entry update20-May-2021
Version number17