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Cellosaurus HT29-16E (CVCL_C763)

[Text version]

Cell line name HT29-16E
Synonyms HT29 16E; HT-29 16E; HT29-Cl.16E; HT29 clone 16E; Cl.16E
Accession CVCL_C763
Resource Identification Initiative To cite this cell line use: HT29-16E (RRID:CVCL_C763)
Comments Misspelling: C1.16E; Occasionally.
Sequence variations Heterozygous for APC p.Glu853Ter (c.2557G>T) (from parent cell line).
Heterozygous for APC p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA) (ClinVar=VCV000428112) (from parent cell line).
Heterozygous for BRAF p.Val600Glu (c.1799T>A) (ClinVar=VCV000013961) (from parent cell line).
Heterozygous for PIK3CA p.Pro449Thr (c.1345C>A) (from parent cell line).
Homozygous for SMAD4 p.Gln311Ter (c.931C>T) (ClinVar=VCV000230663) (from parent cell line).
Homozygous for TP53 p.Arg273His (c.818G>A) (ClinVar=VCV000012366) (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0320 (HT-29)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line

Augeron C., Laboisse C.L.
Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.
Cancer Res. 44:3961-3969(1984)

PubMed=8801204; DOI=10.1136/gut.38.2.240
Jarry A., Vallette G., Branka J.E., Laboisse C.
Direct secretory effect of interleukin-1 via type I receptors in human colonic mucous epithelial cells (HT29-Cl.16E).
Gut 38:240-242(1996)

Other Wikidata; Q54896586
Entry history
Entry creation22-Oct-2012
Last entry update12-Jan-2021
Version number16