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Cellosaurus MM200 (CVCL_C836)

[Text version]

Cell line name MM200
Synonyms MM 200
Accession CVCL_C836
Resource Identification Initiative To cite this cell line use: MM200 (RRID:CVCL_C836)
Comments Omics: CNV analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Skin.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line

Goss P.D., Parsons P.G.
The effect of hyperthermia and melphalan on survival of human fibroblast strains and melanoma cell lines.
Cancer Res. 37:152-156(1977)

PubMed=294576; DOI=10.3109/00313027909059039
Muir P.D., Gunz F.W.
A cytogenetic study of eight human melanoma cell lines.
Pathology 11:597-606(1979)

PubMed=460945; DOI=10.3109/00313027909061945
Pope J.H., Morrison L., Moss D.J., Parsons P.G., Dunne R.M.
Human malignant melanoma cell lines.
Pathology 11:191-195(1979)

Maynard K., Parsons P.G.
Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype.
Cancer Res. 46:5009-5013(1986)

Chenevix-Trench G., Martin N.G., Ellem K.A.O.
Gene expression in melanoma cell lines and cultured melanocytes: correlation between levels of c-src-1, c-myc and p53.
Oncogene 5:1187-1193(1990)

PubMed=7520026; DOI=10.1002/ijc.2910580413
Hersey P., Si Z., Smith M.J., Thomas W.D.
Expression of the co-stimulatory molecule B7 on melanoma cells.
Int. J. Cancer 58:527-532(1994)

PubMed=8980186; DOI=10.1002/(SICI)1097-0215(19961211)68:6<795::AID-IJC18>3.0.CO;2-#
Thomas W.D., Smith M.J., Si Z., Hersey P.
Expression of the co-stimulatory molecule CD40 on melanoma cells.
Int. J. Cancer 68:795-801(1996)

Castellano M., Pollock P.M., Walters M.K., Sparrow L.E., Down L.M., Gabrielli B.G., Parsons P.G., Hayward N.K.
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

Thomas W.D., Hersey P.
TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells.
J. Immunol. 161:2195-2200(1998)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147
Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Pavey S., Johansson P., Packer L., Taylor J., Stark M.S., Pollock P.M., Walker G.J., Boyle G.M., Harper U., Cozzi S.-J., Hansen K., Yudt L., Schmidt C., Hersey P., Ellem K.A.O., O'Rourke M.G.E., Parsons P.G., Meltzer P.S., Ringner M., Hayward N.K.
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152
Stark M.S., Hayward N.K.
Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.
Cancer Res. 67:2632-2642(2007)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Johansson P., Pavey S., Hayward N.K.
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

PubMed=23039341; DOI=10.1186/1476-4598-11-75
Byron S.A., Loch D.C., Wellens C.L., Wortmann A., Wu J., Wang J., Nomoto K., Pollock P.M.
Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status.
Mol. Cancer 11:75.1-75.15(2012)

PubMed=23455323; DOI=10.1038/onc.2013.45
Becker T.M., Boyd S.C., Mijatov B., Gowrishankar K., Snoyman S., Pupo G.M., Scolyer R.A., Mann G.J., Kefford R.F., Zhang X.D., Rizos H.
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor.
Oncogene 33:1158-1166(2014)

Anatomy/cell type resources BTO; BTO:0005717
Encyclopedic resources Wikidata; Q54906077
Gene expression databases GEO; GSM162935
GEO; GSM219446
Polymorphism and mutation databases Cosmic; 889014
Cosmic; 928753
Progenetix; CVCL_C836
Entry history
Entry creation22-Oct-2012
Last entry update23-Sep-2021
Version number19