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Cellosaurus SP-49 (CVCL_D022)

Cell line name SP-49
Synonyms Sp-49; SP49
Accession CVCL_D022
Resource Identification Initiative To cite this cell line use: SP-49 (RRID:CVCL_D022)
Comments Population: Japanese.
Doubling time: 60 hours (PubMed=3121553).
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*02:06,24:02
HLA-BB*56:01,40:02
HLA-CC*04:01,03:04
Class II
HLA-DQDQA1*03:02,03:02
DQB1*03:02,03:02
HLA-DRDRB1*04:05,08:02
Disease Mantle cell lymphoma (NCIt: C4337)
Mantle cell lymphoma (ORDO: Orphanet_52416)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C121 ! SP-50B
CVCL_M655 ! SP-52EB
CVCL_C122 ! SP-53
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=3121553; DOI=10.20772/cancersci1985.78.11_1182
Daibata M., Takasaki M., Hirose S., Kubonishi I., Taguchi H., Ohtsuki Y., Miyoshi I.
Establishment of a new human B cell line carrying t(11;14) chromosome abnormality.
Jpn. J. Cancer Res. 78:1182-1185(1987)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Mestre-Escorihuela C., Rubio-Moscardo F., Richter J.A., Siebert R., Climent J., Fresquet V., Beltran E., Agirre X., Marugan I., Marin M., Rosenwald A., Sugimoto K.-j., Wheat L.M., Karran E.L., Garcia J.F., Sanchez-Verde L., Prosper F., Staudt L.M., Pinkel D., Dyer M.J.S., Martinez-Climent J.A.
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

PubMed=19358282; DOI=10.1002/ijc.24351
Inagaki A., Ishida T., Yano H., Ishii T., Kusumoto S., Ito A., Ri M., Mori F., Ding J.-M., Komatsu H., Iida S., Ueda R.
Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
Int. J. Cancer 125:212-221(2009)

PubMed=24362935; DOI=10.1038/nm.3435
Rahal R., Frick M., Romero R., Korn J.M., Kridel R., Chan F.C., Meissner B., Bhang H.-E.C., Ruddy D., Kauffmann A., Farsidjani A., Derti A., Rakiec D., Naylor T., Pfister E., Kovats S., Kim S., Dietze K., Dorken B., Steidl C., Tzankov A., Hummel M., Monahan J., Morrissey M.P., Fritsch C., Sellers W.R., Cooke V.G., Gascoyne R.D., Lenz G., Stegmeier F.
Pharmacological and genomic profiling identifies NF-kappaB-targeted treatment strategies for mantle cell lymphoma.
Nat. Med. 20:87-92(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D022
Encyclopedic resources Wikidata; Q54955386
Gene expression databases GEO; GSM115806
GEO; GSM1266773
GEO; GSM1266774
Polymorphism and mutation databases Cosmic; 1070709
Cosmic; 2296991
Progenetix; CVCL_D022
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number17