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Cellosaurus HES-2 (CVCL_D093)

Cell line name HES-2
Synonyms hES-2; HES 2; HES2; hES2; ES02; ESIBIOe002-A; ESIBIe002-A
Accession CVCL_D093
Resource Identification Initiative To cite this cell line use: HES-2 (RRID:CVCL_D093)
Comments From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA.
From: Monash University; Melbourne; Australia.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC03-02.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
HLA typing Source: PubMed=16919167
Class I
HLA-AA*02:03,02
HLA-BB*46,48
HLA-CC*01,08
Class II
HLA-DQDQB1*04,06
HLA-DRDRB1*04,15
DRB5*01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_QX78 (ESIBIe002-A-1)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=16919167; WiCell

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S8209,11
D13S3178,11
D16S5399,12
TH017,9
TPOX8,12
vWA18,20

Run an STR similarity search on this cell line
Web pages https://stemcelldb.nih.gov/cellLineDetails.do?id=30
Publications

PubMed=10748519; DOI=10.1038/74447
Reubinoff B.E., Pera M.F., Fong C.-Y., Trounson A.O., Bongso A.
Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.
Nat. Biotechnol. 18:399-404(2000)

PubMed=16919167; DOI=10.1186/1741-7007-4-28
Josephson R., Sykes G.R., Liu Y., Ording C.J., Xu W.-N., Zeng X.-M., Shin S., Loring J.F., Maitra A., Rao M.S., Auerbach J.M.
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F., Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=18772870; DOI=10.1038/nprot.2008.140
Braam S.R., Denning C., Matsa E., Young L.E., Passier R., Mummery C.L.
Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification.
Nat. Protoc. 3:1435-1443(2008)

PubMed=23117585; DOI=10.1016/j.scr.2012.09.002
Mallon B.S., Chenoweth J.G., Johnson K.R., Hamilton R.S., Tesar P.J., Yavatkar A.S., Tyson L.J., Park K., Chen K.G., Fann Y.C., McKay R.D.G.
StemCellDB: the human pluripotent stem cell database at the National Institutes of Health.
Stem Cell Res. 10:57-66(2013)

Cross-references
Cell line collections (Providers) WiCell; es02
Cell line databases/resources hPSCreg; ESIBIe002-A
ISCR; 95
SKIP; SKIP001942
Biological sample resources BioSample; SAMN03471889
Encyclopedic resources Wikidata; Q54882906
Experimental variables resources EFO; EFO_0003048
Gene expression databases GEO; GSM856723
GEO; GSM862740
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number18