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Cellosaurus K562-IMR (CVCL_D201)

[Text version]

Cell line name K562-IMR
Synonyms K562-IM-R; K562 IMR; K562/IMR
Accession CVCL_D201
Resource Identification Initiative To cite this cell line use: K562-IMR (RRID:CVCL_D201)
Comments Selected for resistance to: ChEBI; CHEBI:45783; Imatinib (Gleevec; STI571).
Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line

PubMed=18829496; DOI=10.1158/1078-0432.CCR-08-0461
Okabe S., Tauchi T., Ohyashiki K.
Characteristics of dasatinib- and imatinib-resistant chronic myelogenous leukemia cells.
Clin. Cancer Res. 14:6181-6186(2008)

Other Wikidata; Q54899392
Entry history
Entry creation22-Oct-2012
Last entry update12-Mar-2020
Version number13