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Cellosaurus MDA-MB-231-luc2 (CVCL_D582)

[Text version]

Cell line name MDA-MB-231-luc2
Synonyms MDA-MB-231-Luc2
Accession CVCL_D582
Resource Identification Initiative To cite this cell line use: MDA-MB-231-luc2 (RRID:CVCL_D582)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Discontinued: PerkinElmer/Caliper; Catalog number 124319.
Sequence variations Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0062 (MDA-MB-231)
CVCL_1D89 (MDA-MB-231-luc2-GFP)CVCL_1D92 (MDA-MB-231-luc2-LN)CVCL_1D90 (MDA-MB-231-luc2-tdTomato)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line

Kim J.B., Wong K., Urban K.
Generation of invasive breast cancer cell lines for in vivo imaging.
Cancer Res. 73 Suppl. 1:3908-3908(2013)

Ontologies BTO; BTO:0005172
Other Wikidata; Q54904600
Entry history
Entry creation22-Oct-2012
Last entry update02-Jul-2020
Version number16