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Cellosaurus SK-OV-3/CBP (CVCL_D621)

Cell line name SK-OV-3/CBP
Synonyms SKOV3/CBP; S-car
Accession CVCL_D621
Resource Identification Initiative To cite this cell line use: SK-OV-3/CBP (RRID:CVCL_D621)
Comments Selected for resistance to: ChEBI; CHEBI:31355; Carboplatin (CBP; Paraplatin).
Sequence variations Heterozygous for APC p.Thr1556fs*9 (c.4666delA) (from parent cell line).
Heterozygous for PIK3CA p.His1047Arg (c.3140A>G) (from parent cell line).
Homozygous for TP53 p.Ser90fs*33 (c.267delC) (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line

PubMed=15254775; DOI=10.3892/ijmm.14.2.257
Li L., Luan Y., Wang G., Tang B., Li D., Zhang W., Li X., Zhao J., Ding H., Reed E., Li Q.Q.
Development and characterization of five cell models for chemoresistance studies of human ovarian carcinoma.
Int. J. Mol. Med. 14:257-264(2004)

PubMed=17269733; DOI=10.1021/pr060402r
Yan X.-D., Pan L.-Y., Yuan Y., Lang J.-H., Mao N.
Identification of platinum-resistance associated proteins through proteomic analysis of human ovarian cancer cells and their platinum-resistant sublines.
J. Proteome Res. 6:772-780(2007)

Other Wikidata; Q54954499