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Cellosaurus FM3A FUA169 (CVCL_D688)

[Text version]
Cell line name FM3A FUA169
Synonyms FUA169; FUA 169
Accession CVCL_D688
Resource Identification Initiative To cite this cell line use: FM3A FUA169 (RRID:CVCL_D688)
Comments Characteristics: Compared to the parent cell line, shows a dramatic reduction in lactosylceramide (LacCer), the presence of a ganglioside GM3 and a high activity of CMP-sialic acid:LacCer 2,3-sialosyltransferase (PubMed=7678417).
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/He.
Hierarchy Parent: CVCL_D687 (FM3A F28-7)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=7678417; DOI=10.1016/S0021-9258(18)53983-1
Tsuruoka T., Tsuji T., Nojiri H., Holmes E.H., Hakomori S.-i.
Selection of a mutant cell line based on differential expression of glycosphingolipid, utilizing anti-lactosylceramide antibody and complement.
J. Biol. Chem. 268:2211-2216(1993)

PubMed=8420989; DOI=10.1016/S0021-9258(18)53984-3
Zheng M.-Z., Fang H., Tsuruoka T., Tsuji T., Sasaki T., Hakomori S.-i.
Regulatory role of GM3 ganglioside in alpha 5 beta 1 integrin receptor for fibronectin-mediated adhesion of FUA169 cells.
J. Biol. Chem. 268:2217-2222(1993)

Cross-references
Encyclopedic resources Wikidata; Q54835259
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number8