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Cellosaurus MRC-5V1 (CVCL_D690)

[Text version]

Cell line name MRC-5V1
Synonyms MRC5-V1; MRC5V1
Accession CVCL_D690
Resource Identification Initiative To cite this cell line use: MRC-5V1 (RRID:CVCL_D690)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from sampling site: Fetal lung.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0440 (MRC-5)
Sex of cell Male
Age at sampling 14FW
Category Transformed cell line
Publications

PubMed=6313714; DOI=10.1242/jcs.63.1.77
Huschtscha L.I., Holliday R.
Limited and unlimited growth of SV40-transformed cells from human diploid MRC-5 fibroblasts.
J. Cell Sci. 63:77-99(1983)

PubMed=2821020; DOI=10.1242/jcs.1984.Supplement_6.8
Green M.H.L., Lowe J.E., Arlett C.F., Harcourt S.A., Burke J.F., James M.R., Lehmann A.R., Povey S.M.
A gamma-ray-resistant derivative of an ataxia telangiectasia cell line obtained following DNA-mediated gene transfer.
J. Cell Sci. Suppl. 6:127-137(1987)

PubMed=2903889; DOI=10.1080/09553008814552321
Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V.
Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes.
Int. J. Radiat. Biol. 54:911-928(1988)

PubMed=3180052
Lehmann A.R., Willis A.E., Broughton B.C., James M.R., Steingrimsdottir H., Harcourt S.A., Arlett C.F., Lindahl T.
Relation between the human fibroblast strain 46BR and cell lines representative of Bloom's syndrome.
Cancer Res. 48:6343-6347(1988)

PubMed=8055625; DOI=10.1093/carcin/15.8.1493
Mezzina M., Eveno E., Chevallier-Lagente O., Benoit A., Carreau M., Vermeulen W., Hoeijmakers J.H.J., Stefanini M., Lehmann A.R., Weber C.A., Sarasin A.
Correction by the ERCC2 gene of UV sensitivity and repair deficiency phenotype in a subset of trichothiodystrophy cells.
Carcinogenesis 15:1493-1498(1994)

PubMed=7563073; DOI=10.1006/jmbi.1995.0519
Marionnet C., Benoit A., Benhamou S., Sarasin A., Stary A.
Characteristics of UV-induced mutation spectra in human XP-D/ERCC2 gene-mutated xeroderma pigmentosum and trichothiodystrophy cells.
J. Mol. Biol. 252:550-562(1995)

PubMed=8824772; DOI=10.1016/0300-9084(95)90011-x
Eveno E., Quilliet X., Chevallier-Lagente O., Daya-Grosjean L., Stary A., Zeng L., Benoit A., Savini E., Ciarrocchi G., Kannouche P., Salles B., Sarasin A., Mezzina M.
Stable SV40-transformation and characterisation of some DNA repair properties of fibroblasts from a trichothiodystrophy patient.
Biochimie 77:906-912(1995)

PubMed=21528266; DOI=10.3892/ijo.11.4.717
Kolettas E., Spandidos D.A., Rosenberger R.F.
SV40-transformation of embryonic human diploid fibroblasts results in multiple molecular changes.
Int. J. Oncol. 11:717-725(1997)

PubMed=16714754; DOI=10.1259/bjr/83726649
Arlett C.F., Plowman P.N., Rogers P.B., Parris C.N., Abbaszadeh F., Green M.H.L., McMillan T.J., Bush C., Foray N., Lehmann A.R.
Clinical and cellular ionizing radiation sensitivity in a patient with xeroderma pigmentosum.
Br. J. Radiol. 79:510-517(2006)

Cross-references
Anatomy/cell type resources BTO; BTO:0005066
Encyclopedic resources Wikidata; Q54906594
Entry history
Entry creation22-Oct-2012
Last entry update02-Jul-2020
Version number12