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Cellosaurus FM3A SX9 (CVCL_D700)

[Text version]
Cell line name FM3A SX9
Synonyms SX9; SX-9
Accession CVCL_D700
Resource Identification Initiative To cite this cell line use: FM3A SX9 (RRID:CVCL_D700)
Comments Characteristics: Radiation-sensitive. The parent cell line was irradiated with 2 Gy and this clone was hypersensitive to X-ray killing (PubMed=2426230).
Doubling time: 17.7 hours (PubMed=2426230); 20 hours (PubMed=7528891).
Selected for resistance to: NCIt; C17262; X-Ray.
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Sequence variations
  • Mutation; MGI; MGI:104779; Prkdc; Simple; p.Leu3191Pro (c.9572T>C); Zygosity=Unspecified (PubMed=9582343).
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/He.
Hierarchy Parent: CVCL_S164 (FM3A SR-1)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=2426230; DOI=10.20772/cancersci1985.77.5_456
Sato K., Ito A., Shiomi T., Hama-Inaba H., Ishikawa H., Yoshizumi T., Nakazawa T.
X-ray-sensitive mutants of mouse mammary carcinoma cells are hypersensitive to bleomycin and hydrogen peroxide.
Jpn. J. Cancer Res. 77:456-461(1986)

PubMed=7528891; DOI=10.1016/0921-8777(94)00036-6
Warters R.L., Barrows L.R., Chen D.J.
DNA double-strand break repair in two radiation-sensitive mouse mammary carcinoma cell lines.
Mutat. Res. 336:1-7(1995)

PubMed=9582343; DOI=10.1074/jbc.273.21.13058
Fukumura R., Araki R., Fujimori A., Mori M., Saito T., Watanabe F., Sarashi M., Itsukaichi H., Eguchi-Kasai K., Sato K., Tatsumi K., Abe M.
Murine cell line SX9 bearing a mutation in the DNA-PKcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint.
J. Biol. Chem. 273:13058-13064(1998)

Cross-references
Encyclopedic resources Wikidata; Q54971263
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number11