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Cellosaurus L835 (CVCL_D708)

[Text version]
Cell line name L835
Accession CVCL_D708
Resource Identification Initiative To cite this cell line use: L835 (RRID:CVCL_D708)
Comments Omics: Array-based CGH.
Miscellaneous: STR profile from personal communication of Cleton-Jansen A.-M.
Derived from site: Metastatic; Bone, left distal radius; UBERON=UBERON_0004407.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=22928481).
  • Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (PubMed=22928481).
Disease Secondary chondrosarcoma (NCIt: C27482)
Chondrosarcoma (ORDO: Orphanet_55880)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO11
D5S81812
D7S82011,12
D13S3178,13
D16S53911
D21S1128,29
TH019.3
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=22057234; DOI=10.1038/ng.1004
Pansuriya T.C., van Eijk R., d'Adamo P., van Ruler M.A.J.H., Kuijjer M.L., Oosting J., Cleton-Jansen A.-M., van Oosterwijk J.G., Verbeke S.L.J., Meijer D., van Wezel T., Nord K.H., Sangiorgi L., Toker B., Liegl-Atzwanger B., San-Julian M., Sciot R., Limaye N., Kindblom L.-G., Daugaard S., Godfraind C., Boon L.M., Vikkula M., Kurek K.C., Szuhai K., French P.J., Bovee J.V.M.G.
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.
Nat. Genet. 43:1256-1261(2011)

PubMed=22928481; DOI=10.1186/1471-2407-12-375
van Oosterwijk J.G., de Jong D., van Ruler M.A.J.H., Hogendoorn P.C.W., Dijkstra P.D.S., van Rijswijk C.S.P., Machado I., Llombart-Bosch A., Szuhai K., Bovee J.V.M.G.
Three new chondrosarcoma cell lines: one grade III conventional central chondrosarcoma and two dedifferentiated chondrosarcomas of bone.
BMC Cancer 12:375.1-375.10(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D708
Encyclopedic resources Wikidata; Q54901842
Polymorphism and mutation databases Cosmic; 1602479
Cosmic; 1755114
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number18