Cellosaurus MOLM-13-RES (CVCL_D779)

Cell line name MOLM-13-RES
Accession CVCL_D779
Resource Identification Initiative To cite this cell line use: MOLM-13-RES (RRID:CVCL_D779)
Comments Selected for resistance to: ChEBI; CHEBI:90237; Tandutinib (MLN518; CT53518).
Derived from sampling site: Peripheral blood.
Sequence variations FLT3 internal tandem duplication (FLT3-ITD) (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2119 (MOLM-13)
Children:
CVCL_D780 (MOLM-13-RES-AC)
Sex of cell Male
Age at sampling 20Y
Category Cancer cell line
Publications

PubMed=22354205; DOI=10.1038/leu.2012.52
Moore A.S., Faisal A., Gonzalez de Castro D., Bavetsias V., Sun C., Atrash B., Valenti M., de Haven Brandon A., Avery S., Mair D., Mirabella F., Swansbury J., Pearson A.D.J., Workman P., Blagg J., Raynaud F.I., Eccles S.A., Linardopoulos S.
Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns.
Leukemia 26:1462-1470(2012)

Cross-references
Polymorphism and mutation databases Cosmic; 1741689