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Cellosaurus HPK-1A-ras (CVCL_D891)

[Text version]

Cell line name HPK-1A-ras
Synonyms HPK-1A/ras; HPK1A-ras; KiMSV/HPK-1A; K-ras/HPK-1A
Accession CVCL_D891
Resource Identification Initiative To cite this cell line use: HPK-1A-ras (RRID:CVCL_D891)
Comments Characteristics: Contains several complete HPV16 genomes arranged in a head-to-tail fashion and integrated at a single chromosomal site.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Transformant: NCBI_TaxID; 11808; Kirsten murine sarcoma virus (Ki-MSV).
Derived from sampling site: Foreskin; skin; epidermis; keratinocyte.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D890 (HPK-1A)
Sex of cell Male
Category Transformed cell line

PubMed=2556855; DOI=10.1016/0042-6822(89)90595-3
Durst M., Gallahan D., Jay G., Rhim J.S.
Glucocorticoid-enhanced neoplastic transformation of human keratinocytes by human papillomavirus type 16 and an activated ras oncogene.
Virology 173:767-771(1989)

Henderson J., Sebag M., Rhim J.S., Goltzman D., Kremer R.
Dysregulation of parathyroid hormone-like peptide expression and secretion in a keratinocyte model of tumor progression.
Cancer Res. 51:6521-6528(1991)

Ontologies BTO; BTO:0005275
Other Wikidata; Q54890292
Entry history
Entry creation22-Oct-2012
Last entry update12-Jan-2021
Version number8