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Cellosaurus HPK-1A-ras (CVCL_D891)

[Text version]
Cell line name HPK-1A-ras
Synonyms HPK-1A/ras; HPK1A-ras; KiMSV/HPK-1A; K-ras/HPK-1A
Accession CVCL_D891
Resource Identification Initiative To cite this cell line use: HPK-1A-ras (RRID:CVCL_D891)
Comments Virology: Contains several complete HPV16 genomes arranged in a head-to-tail fashion and integrated at a single chromosomal site.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Transformant: NCBI_TaxID; 11808; Kirsten murine sarcoma virus (Ki-MSV).
Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D890 (HPK-1A)
Sex of cell Male
Category Transformed cell line
Publications

PubMed=2556855; DOI=10.1016/0042-6822(89)90595-3
Durst M., Gallahan D., Jay G., Rhim J.S.
Glucocorticoid-enhanced neoplastic transformation of human keratinocytes by human papillomavirus type 16 and an activated ras oncogene.
Virology 173:767-771(1989)

DOI=10.1007/978-1-4612-0411-4_3
Allen-Hoffmann B.L., Sheibani N., Hatfield J.S., Rhim J.S.
Use of immortalized human keratinocytes for the study of squamous differentiation and mutagenesis.
(In) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.25-34; Humana Press; New York (1990)

PubMed=1742725
Henderson J., Sebag M., Rhim J.S., Goltzman D., Kremer R.
Dysregulation of parathyroid hormone-like peptide expression and secretion in a keratinocyte model of tumor progression.
Cancer Res. 51:6521-6528(1991)

Cross-references
Anatomy/cell type resources BTO; BTO:0005275
Encyclopedic resources Wikidata; Q54890292
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number12