ID   HPK-1A-ras
AC   CVCL_D891
SY   HPK-1A/ras; HPK1A-ras; KiMSV/HPK-1A; K-ras/HPK-1A
DR   BTO; BTO:0005275
DR   Wikidata; Q54890292
RX   DOI=10.1007/978-1-4612-0411-4_3;
RX   PubMed=1742725;
RX   PubMed=2556855;
CC   Virology: Contains several complete HPV16 genomes arranged in a head-to-tail fashion and integrated at a single chromosomal site.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Transformant: NCBI_TaxID; 11808; Kirsten murine sarcoma virus (Ki-MSV).
CC   Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_D890 ! HPK-1A
SX   Male
CA   Transformed cell line
DT   Created: 22-10-12; Last updated: 29-06-23; Version: 12
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RX   DOI=10.1007/978-1-4612-0411-4_3;
RA   Allen-Hoffmann B.L., Sheibani N., Hatfield J.S., Rhim J.S.;
RT   "Use of immortalized human keratinocytes for the study of squamous
RT   differentiation and mutagenesis.";
RL   (In) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.25-34; Humana Press; New York (1990).
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RX   PubMed=1742725;
RA   Henderson J., Sebag M., Rhim J.S., Goltzman D., Kremer R.;
RT   "Dysregulation of parathyroid hormone-like peptide expression and
RT   secretion in a keratinocyte model of tumor progression.";
RL   Cancer Res. 51:6521-6528(1991).
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RX   PubMed=2556855; DOI=10.1016/0042-6822(89)90595-3;
RA   Durst M., Gallahan D., Jay G., Rhim J.S.;
RT   "Glucocorticoid-enhanced neoplastic transformation of human
RT   keratinocytes by human papillomavirus type 16 and an activated ras
RT   oncogene.";
RL   Virology 173:767-771(1989).
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