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Cellosaurus JJ012-TS4 (CVCL_D901)

Cell line name JJ012-TS4
Accession CVCL_D901
Resource Identification Initiative To cite this cell line use: JJ012-TS4 (RRID:CVCL_D901)
Comments Sequence variation: Heterozygous for IDH1 p.Arg132Gly (from parent cell line).
Transfected with: HGNC; 220; ADAMTS4.
Disease Chondrosarcoma (NCIt: C2946)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D605 (JJ012)
Sex of cell Male
Category Cancer cell line

PubMed=11796708; DOI=10.1074/jbc.M107443200
Gao G., Westling J., Thompson V.P., Howell T.D., Gottschall P.E., Sandy J.D.
Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation.
J. Biol. Chem. 277:11034-11041(2002)

PubMed=14701864; DOI=10.1074/jbc.M312100200
Gao G., Plaas A., Thompson V.P., Jin S., Zuo F., Sandy J.D.
ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1.
J. Biol. Chem. 279:10042-10051(2004)

Ontologies BTO; BTO:0003043