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Cellosaurus H1G1.1c3 (CVCL_DC19)

[Text version]
Cell line name H1G1.1c3
Accession CVCL_DC19
Resource Identification Initiative To cite this cell line use: H1G1.1c3 (RRID:CVCL_DC19)
Comments Biotechnology: Cell line developed for CAFLUX (Chemically Activated FLUorescence eXpression) bioassay. CAFLUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
Characteristics: Acts through the activation of a EGFP gene under the control of dioxin-response elements (DREs).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57L.
Hierarchy Parent: CVCL_0328 (Hepa-1c1c7)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=11812924; DOI=10.1093/toxsci/65.2.200
Nagy S.R., Sanborn J.R., Hammock B.D., Denison M.S.
Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detection and characterization of ah receptor agonists.
Toxicol. Sci. 65:200-210(2002)

PubMed=15096657; DOI=10.1002/biof.5520200102
Han D., Nagy S.R., Denison M.S.
Comparison of recombinant cell bioassays for the detection of Ah receptor agonists.
BioFactors 20:11-22(2004)

PubMed=21394221; DOI=10.1007/s11426-010-0142-8
Zhao B., Baston D.S., Khan E., Sorrentino C., Denison M.S.
Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds.
Sci. China Chem. 53:1010-1016(2010)

Cross-references
Encyclopedic resources Wikidata; Q54871984
Entry history
Entry creation13-Jul-2016
Last entry update29-Jun-2023
Version number9