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Cellosaurus H1L6.1c2 (CVCL_DC22)

[Text version]
Cell line name H1L6.1c2
Accession CVCL_DC22
Resource Identification Initiative To cite this cell line use: H1L6.1c2 (RRID:CVCL_DC22)
Comments Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57L.
Hierarchy Parent: CVCL_0328 (Hepa-1c1c7)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=15096657; DOI=10.1002/biof.5520200102
Han D., Nagy S.R., Denison M.S.
Comparison of recombinant cell bioassays for the detection of Ah receptor agonists.
BioFactors 20:11-22(2004)

PubMed=21394221; DOI=10.1007/s11426-010-0142-8
Zhao B., Baston D.S., Khan E., Sorrentino C., Denison M.S.
Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds.
Sci. China Chem. 53:1010-1016(2010)

Cross-references
Encyclopedic resources Wikidata; Q54871988
Entry history
Entry creation13-Jul-2016
Last entry update29-Jun-2023
Version number9