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Cellosaurus H1L7.5c1 (CVCL_DC24)

Cell line name H1L7.5c1
Accession CVCL_DC24
Resource Identification Initiative To cite this cell line use: H1L7.5c1 (RRID:CVCL_DC24)
Comments Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57L.
Hierarchy Parent: CVCL_0328 (Hepa-1c1c7)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=21872055; DOI=10.1016/j.talanta.2011.07.042
Van Langenhove K., Croes K., Denison M.S., Elskens M., Baeyens W.
The CALUX bio-assay: analytical comparison between mouse hepatoma cell lines with a low (H1L6.1c3) and high (H1L7.5c1) number of dioxin response elements.
Talanta 85:2039-2046(2011)

Cross-references
Encyclopedic resources Wikidata; Q54871990
Entry history
Entry creation13-Jul-2016
Last entry update29-Jun-2023
Version number9