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Cellosaurus H4G1.1c2 (CVCL_DC26)

Cell line name H4G1.1c2
Accession CVCL_DC26
Resource Identification Initiative To cite this cell line use: H4G1.1c2 (RRID:CVCL_DC26)
Comments Biotechnology: Cell line developed for CAFLUX (Chemically Activated FLUorescence eXpression) bioassay. CAFLUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists.
Characteristics: Acts through the activation of a EGFP gene under the control of dioxin-response elements (DREs).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Rat hepatocellular carcinoma (NCIt: C60416)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: AxC.
Hierarchy Parent: CVCL_0284 (H4-II-E)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=21394221; DOI=10.1007/s11426-010-0142-8
Zhao B., Baston D.S., Khan E., Sorrentino C., Denison M.S.
Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds.
Sci. China Chem. 53:1010-1016(2010)

Cross-references
Encyclopedic resources Wikidata; Q54872156
Entry history
Entry creation13-Jul-2016
Last entry update29-Jun-2023
Version number8