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Cellosaurus MCF-7.5C (CVCL_DC70)

[Text version]

Cell line name MCF-7.5C
Synonyms MCF-7 clone 5C; 5C
Accession CVCL_DC70
Resource Identification Initiative To cite this cell line use: MCF-7.5C (RRID:CVCL_DC70)
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

PubMed=1301400; DOI=10.1016/0303-7207(92)90104-E
Jiang S.-Y., Wolf D.M., Yingling J.M., Chang C., Jordan V.C.
An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol.
Mol. Cell. Endocrinol. 90:77-86(1992)

Levenson A.S., Jordan V.C.
MCF-7: the first hormone-responsive breast cancer cell line.
Cancer Res. 57:3071-3078(1997)

Other Wikidata; Q54904329
Entry history
Entry creation13-Jul-2016
Last entry update02-Jul-2020
Version number6