ID   293LAP10
SY   293Lap10
DR   ATCC; CRL-12586
DR   Wikidata; Q54584124
RX   Patent=WO2000006751A2;
RX   PubMed=10073694;
CC   Transfected with: UniProtKB; P03023; E.coli lacI (modified version LAP348 with at the N-terminal a nuclear localization signal from SV40 T antigen and at the C-terminal the transactivator domain from HSV-1 VP16/Vmw65).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Discontinued: ATCC; CRL-12586; probable.
CC   Derived from sampling site: Fetal kidney.
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 13-07-16; Last updated: 29-10-20; Version: 5
RX   Patent=WO2000006751A2;
RA   Graham F.L., Prevec L., Matthews D.A.;
RT   "Repressor proteins producing cell lines for the propagation of
RT   vectors.";
RL   Patent number WO2000006751A2, 10-Feb-2000.
RX   PubMed=10073694; DOI=10.1099/0022-1317-80-2-345;
RA   Matthews D.A., Cummings D., Evelegh C., Graham F.L., Prevec L.;
RT   "Development and use of a 293 cell line expressing lac repressor for
RT   the rescue of recombinant adenoviruses expressing high levels of
RT   rabies virus glycoprotein.";
RL   J. Gen. Virol. 80:345-353(1999).