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Cellosaurus HT-29/cl.f8 (CVCL_DE12)

Cell line name HT-29/cl.f8
Synonyms HT-29 cl.F8; HT29.f8; HT29.F8
Accession CVCL_DE12
Resource Identification Initiative To cite this cell line use: HT-29/cl.f8 (RRID:CVCL_DE12)
Comments Population: Caucasian.
Characteristics: Spontaneously polarizing cell line.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0320 (HT-29)
Sex of cell Female
Age at sampling 44Y
Category Cancer cell line
Publications

PubMed=15780006; DOI=10.1290/04100061.1
Mitchell D.M., Ball J.M.
Characterization of a spontaneously polarizing HT-29 cell line, HT-29/cl.f8.
In Vitro Cell. Dev. Biol. Anim. 40:297-302(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_DE12
Encyclopedic resources Wikidata; Q54896528
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number18