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Cellosaurus HepBHAe82 (CVCL_DF32)

[Text version]

Cell line name HepBHAe82
Synonyms HepBHAe-82
Accession CVCL_DF32
Resource Identification Initiative To cite this cell line use: HepBHAe82 (RRID:CVCL_DF32)
Comments Biotechnology: Used for a bioassay to detect HBV covalently closed circular (ccc) DNA.
Characteristics: Transfected with an in-frame influenza hemagglutinin (HA) epitope tag into the precore domain of hepatitis B virus (HBV) e antigen (HBeAg).
Sequence variations NRAS p.Gln61Leu (c.182A>T) (ClinVar=VCV000375874) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line

PubMed=27185623; DOI=10.1016/j.antiviral.2016.05.005
Cai D., Wang X., Yan R., Mao R., Liu Y., Ji C., Cuconati A., Guo H.
Establishment of an inducible HBV stable cell line that expresses cccDNA-dependent epitope-tagged HBeAg for screening of cccDNA modulators.
Antiviral Res. 132:26-37(2016)

Other Wikidata; Q54882837
Entry history
Entry creation13-Jul-2016
Last entry update02-Jul-2020
Version number10