ID   HepBHAe82
AC   CVCL_DF32
SY   HepBHAe-82
DR   cancercelllines; CVCL_DF32
DR   Wikidata; Q54882837
RX   PubMed=27185623;
CC   Population: Caucasian.
CC   Biotechnology: Used for a bioassay to detect HBV covalently closed circular (ccc) DNA.
CC   Characteristics: Transfected with an in-frame influenza hemagglutinin (HA) epitope tag into the precore domain of hepatitis B virus (HBV) e antigen (HBeAg).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 05-10-23; Version: 16
//
RX   PubMed=27185623; DOI=10.1016/j.antiviral.2016.05.005;
RA   Cai D.-W., Wang X.-H., Yan R., Mao R.-C., Liu Y.-J., Ji C.-H.,
RA   Cuconati A., Guo H.-T.;
RT   "Establishment of an inducible HBV stable cell line that expresses
RT   cccDNA-dependent epitope-tagged HBeAg for screening of cccDNA
RT   modulators.";
RL   Antiviral Res. 132:26-37(2016).
//