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Cellosaurus NGC-0295 (CVCL_DF66)

[Text version]

Cell line name NGC-0295
Synonyms NGC0295
Accession CVCL_DF66
Resource Identification Initiative To cite this cell line use: NGC-0295 (RRID:CVCL_DF66)
Comments Biotechnology: Used in NsG0202, an encapsulated cell biodelivery device capable of local delivery of NGF to the brain so at to treat the cognitive decline in Alzheimer disease patients.
Transfected with: HGNC; 7808; NGF.
Derived from sampling site: Eye; retinal pigment epithelium.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0145 (ARPE-19)
Sex of cell Male
Age at sampling 19Y
Category Spontaneously immortalized cell line

PubMed=20664524; DOI=10.1038/mt.2010.154
Fjord-Larsen L., Kusk P., Tornoe J., Juliusson B., Torp M., Bjarkam C.R., Nielsen M.S., Handberg A., Sorensen J.C.H., Wahlberg L.U.
Long-term delivery of nerve growth factor by encapsulated cell biodelivery in the Gottingen minipig basal forebrain.
Mol. Ther. 18:2164-2172(2010)

PubMed=22113314; DOI=10.1038/gt.2011.178
Fjord-Larsen L., Kusk P., Emerich D.F., Thanos C., Torp M., Bintz B., Tornoe J., Johnsen A.H., Wahlberg L.U.
Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer.
Gene Ther. 19:1010-1017(2012)

PubMed=22655593; DOI=10.3171/2012.2.JNS11714
Wahlberg L.U., Lind G., Almqvist P.M., Kusk P., Tornoe J., Juliusson B., Soderman M., Sellden E., Seiger A., Eriksdotter-Jonhagen M., Linderoth B.
Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: a technology platform for restorative neurosurgery.
J. Neurosurg. 117:340-347(2012)

Other Wikidata; Q54930462
Entry history
Entry creation13-Jul-2016
Last entry update12-Mar-2020
Version number6