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Cellosaurus L56Br-C1 (CVCL_DF84)

[Text version]
Cell line name L56Br-C1
Synonyms L56-BR-C1; L56BrC1
Accession CVCL_DF84
Resource Identification Initiative To cite this cell line use: L56Br-C1 (RRID:CVCL_DF84)
Comments Characteristics: Established from the xenograft L56Br-X1 (PubMed=12649339).
Omics: Array-based CGH.
Derived from site: Metastatic; Axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; 1100; BRCA1; Simple; p.Gln563Ter (c.1687C>T) (1806C>T); ClinVar=VCV000037426; Zygosity=Hemizygous (PubMed=12649339).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser215Ile (c.644G>T); ClinVar=VCV000376660; Zygosity=Unspecified (PubMed=12649339).
Disease BRCA1-associated hereditary breast and ovarian cancer syndrome (NCIt: C36100)
Breast carcinoma (NCIt: C4872)
Hereditary breast and ovarian cancer syndrome (ORDO: Orphanet_145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=11846806; DOI=10.1046/j.0014-2956.2001.02744.x
Hegardt C., Johannsson O.T., Oredsson S.M.
Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N(1),N(11)-diethylnorspermine.
Eur. J. Biochem. 269:1033-1039(2002)

PubMed=12649339; DOI=10.1097/01.LAB.0000060030.10652.8C
Johannsson O.T., Staff S., Vallon-Christersson J., Kytola S., Gudjonsson T., Rennstam K., Hedenfalk I.A., Adeyinka A., Kjellen E., Wennerberg J., Baldetorp B., Petersen O.W., Olsson H., Oredsson S.M., Isola J., Borg A.
Characterization of a novel breast carcinoma xenograft and cell line derived from a BRCA1 germ-line mutation carrier.
Lab. Invest. 83:387-396(2003)

PubMed=17334996; DOI=10.1002/gcc.20438
Jonsson G., Staaf J., Olsson E., Heidenblad M., Vallon-Christersson J., Osoegawa K., de Jong P.J., Oredsson S.M., Ringner M., Hoglund M., Borg A.
High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization.
Genes Chromosomes Cancer 46:543-558(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_DF84
Anatomy/cell type resources BTO; BTO:0004832
Encyclopedic resources Wikidata; Q54901048
Gene expression databases GEO; GSM155216
Polymorphism and mutation databases Progenetix; CVCL_DF84
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number10