Cellosaurus MDA-MB-468GFP (CVCL_DH83)

Cell line name MDA-MB-468GFP
Synonyms 468GFP
Accession CVCL_DH83
Resource Identification Initiative To cite this cell line use: MDA-MB-468GFP (RRID:CVCL_DH83)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Omics: CNV analysis.
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0419 (MDA-MB-468)
Children: CVCL_M372 (MDA-MB-468LN)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=16170671; DOI=10.1007/s10585-005-0745-1
Vantyghem S.A., Allan A.L., Postenka C.O., Al-Katib W., Keeney M., Tuck A.B., Chambers A.F.
A new model for lymphatic metastasis: development of a variant of the MDA-MB-468 human breast cancer cell line that aggressively metastasizes to lymph nodes.
Clin. Exp. Metastasis 22:351-361(2005)

PubMed=20084286; DOI=10.1371/journal.pone.0008665
Andrews J., Kennette W., Pilon J., Hodgson A., Tuck A.B., Chambers A.F., Rodenhiser D.I.
Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number.
PLoS ONE 5:E8665-E8665(2010)

Cross-references
Gene expression databases GEO; GSM390975
GEO; GSM390978