Cellosaurus HCC827 PFR6 (CVCL_DH96)

Cell line name HCC827 PFR6
Synonyms HCC827 PFR-6
Accession CVCL_DH96
Resource Identification Initiative To cite this cell line use: HCC827 PFR6 (RRID:CVCL_DH96)
Comments Selected for resistance to: ChEBI; CHEBI:132268; Dacomitinib (PF-00299804).
Sequence variation: EGFR p.Glu746_Ala750del (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2063 (HCC827)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=20129249; DOI=10.1016/j.ccr.2009.11.022
Turke A.B., Zejnullahu K., Wu Y.-L., Song Y., Dias-Santagata D., Lifshits E., Toschi L., Rogers A., Mok T., Sequist L., Lindeman N.I., Murphy C., Akhavanfard S., Yeap B.Y., Xiao Y., Capelletti M., Iafrate A.J., Lee C., Christensen J.G., Engelman J.A., Janne P.A.
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.
Cancer Cell 17:77-88(2010)

Cross-references
Gene expression databases GEO; GSM466330