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Cellosaurus NCI-H3255GR (CVCL_DI55)

[Text version]
Cell line name NCI-H3255GR
Synonyms H3255GR; H3255 GR
Accession CVCL_DI55
Resource Identification Initiative To cite this cell line use: NCI-H3255GR (RRID:CVCL_DI55)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:49668; Gefitinib (ZD1839; Iressa).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6831 (NCI-H3255)
Children:
CVCL_DI56 (NCI-H3255DR)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
Publications

PubMed=16906227; DOI=10.1172/JCI28656
Engelman J.A., Mukohara T., Zejnullahu K., Lifshits E., Borras A.M., Gale C.-M., Naumov G.N., Yeap B.Y., Jarrell E., Sun J., Tracy S., Zhao X.-J., Heymach J.V., Johnson B.E., Cantley L.C., Janne P.A.
Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer.
J. Clin. Invest. 116:2695-2706(2006)

Cross-references
Encyclopedic resources Wikidata; Q54908038
Polymorphism and mutation databases Cosmic; 1128246
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number5