Cellosaurus NCI-H3255GR (CVCL_DI55)

Cell line name NCI-H3255GR
Synonyms H3255GR; H3255 GR
Accession CVCL_DI55
Resource Identification Initiative To cite this cell line use: NCI-H3255GR (RRID:CVCL_DI55)
Comments Selected for resistance to: ChEBI; CHEBI:49668; Gefitinib (ZD1839; Iressa).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6831 (NCI-H3255)
Sex of cell Female
Category Cancer cell line

PubMed=16906227; DOI=10.1172/JCI28656
Engelman J.A., Mukohara T., Zejnullahu K., Lifshits E., Borras A.M., Gale C.M., Naumov G.N., Yeap B.Y., Jarrell E., Sun J., Tracy S., Zhao X., Heymach J.V., Johnson B.E., Cantley L.C., Janne P.A.
Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer.
J. Clin. Invest. 116:2695-2706(2006)

Polymorphism and mutation databases Cosmic; 1128246