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Cellosaurus NCI-H3255DR (CVCL_DI56)

[Text version]
Cell line name NCI-H3255DR
Synonyms H3255DR
Accession CVCL_DI56
Resource Identification Initiative To cite this cell line use: NCI-H3255DR (RRID:CVCL_DI56)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:132268; Dacomitinib (PF-00299804).
Selected for resistance to: ChEBI; CHEBI:49668; Gefitinib (ZD1839; Iressa).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DI55 (NCI-H3255GR)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
Publications

PubMed=20118985; DOI=10.1038/onc.2009.526
Ercan D., Zejnullahu K., Yonesaka K., Xiao Y., Capelletti M., Rogers A., Lifshits E., Brown A., Lee C., Christensen J.G., Kwiatkowski D.J., Engelman J.A., Janne P.A.
Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor.
Oncogene 29:2346-2356(2010)

Cross-references
Encyclopedic resources Wikidata; Q54908037
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number5