Cell line name | PC-9/IR |
---|---|
Synonyms | PC-9-IR; PC9-IR; PC9/IR; PC9IR; PC9/gef |
Accession | CVCL_DP47 |
Resource Identification Initiative | To cite this cell line use: PC-9/IR (RRID:CVCL_DP47) |
Comments | Population: Japanese. Selected for resistance to: ChEBI; CHEBI:49668; Gefitinib (ZD1839; Iressa). Omics: Deep membrane proteome analysis. Omics: Deep phosphoproteome analysis. |
Sequence variations | EGFR p.Glu746_Ala750del (c.2235_2249del15) (ClinVar=VCV000163343) (from parent cell line).Homozygous for TP53 p.Arg248Gln (c.743G>A) (ClinVar=VCV000012356) (from parent cell line). |
Disease | Lung adenocarcinoma (NCIt: C3512) Derived from metastatic site: Lymph node. |
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
Hierarchy | Parent: CVCL_B260 (PC-9) |
Sex of cell | Male |
Age at sampling | 45Y |
Category | Cancer cell line |
Publications | PubMed=26202522; DOI=10.1021/acs.jproteome.5b00477 PubMed=26554430; DOI=10.1021/acs.analchem.5b03639 PubMed=28290473; DOI=10.1038/srep44021 |
Cross-references | |
Other | Wikidata; Q54938501 |
Proteomic databases | PRIDE; PXD001548
PRIDE; PXD002224 |
Entry history | |
Entry creation | 13-Jul-2016 |
Last entry update | 12-Jan-2021 |
Version number | 10 |