Cellosaurus LAMA84-rn (CVCL_DP54)

Cell line name LAMA84-rn
Accession CVCL_DP54
Resource Identification Initiative To cite this cell line use: LAMA84-rn (RRID:CVCL_DP54)
Comments Selected for resistance to: ChEBI; CHEBI:52172; Nilotinib (AMN107; Tasigna).
Derived from sampling site: Peripheral blood.
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0388 (LAMA-84)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=19047160; DOI=10.1158/0008-5472.CAN-08-1008
Mahon F.-X., Hayette S., Lagarde V., Belloc F., Turcq B., Nicolini F., Belanger C., Manley P.W., Leroy C., Etienne G., Roche S., Pasquet J.-M.
Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression.
Cancer Res. 68:9809-9816(2008)