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Cellosaurus SupB15RT (CVCL_DR65)

[Text version]
Cell line name SupB15RT
Accession CVCL_DR65
Resource Identification Initiative To cite this cell line use: SupB15RT (RRID:CVCL_DR65)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:45783; Imatinib (Gleevec; STI571).
Omics: HLA class I peptidome analysis by proteomics.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
Disease Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C68659)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0103 (SUP-B15)
Sex of cell Male
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=25576301; DOI=10.1074/mcp.M114.042812
Bassani-Sternberg M., Pletscher-Frankild S., Jensen L.J., Mann M.
Mass spectrometry of human leukocyte antigen class I peptidomes reveals strong effects of protein abundance and turnover on antigen presentation.
Mol. Cell. Proteomics 14:658-673(2015)

Cross-references
Encyclopedic resources Wikidata; Q54970907
Proteomic databases PRIDE; PXD000394
Entry history
Entry creation13-Jul-2016
Last entry update29-Jun-2023
Version number10