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Cellosaurus MCF-7/Twist (CVCL_DR99)

[Text version]

Cell line name MCF-7/Twist
Accession CVCL_DR99
Resource Identification Initiative To cite this cell line use: MCF-7/Twist (RRID:CVCL_DR99)
Comments Transfected with: HGNC; 12428; TWIST1.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

PubMed=16322226; DOI=10.1158/0008-5472.CAN-05-0712
Mironchik Y., Winnard P.T. Jr., Vesuna F., Kato Y., Wildes F., Pathak A.P., Kominsky S.L., Artemov D., Bhujwalla Z., Van Diest P., Burger H., Glackin C., Raman V.
Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer.
Cancer Res. 65:10801-10809(2005)

PubMed=20019840; DOI=10.1593/neo.91084
Vesuna F., Lisok A., Kimble B., Raman V.
Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression.
Neoplasia 11:1318-1328(2009)

Other Wikidata; Q54904396
Entry history
Entry creation13-Jul-2016
Last entry update02-Jul-2020
Version number6