ID   MCF-7/Twist
AC   CVCL_DR99
DR   cancercelllines; CVCL_DR99
DR   Wikidata; Q54904396
RX   PubMed=16322226;
RX   PubMed=20019840;
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: HGNC; 12428; TWIST1.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 05-10-23; Version: 12
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RX   PubMed=16322226; DOI=10.1158/0008-5472.CAN-05-0712;
RA   Mironchik Y., Winnard P.T. Jr., Vesuna F., Kato Y., Wildes F.,
RA   Pathak A.P., Kominsky S.L., Artemov D., Bhujwalla Z., Van Diest P.,
RA   Burger H., Glackin C., Raman V.;
RT   "Twist overexpression induces in vivo angiogenesis and correlates with
RT   chromosomal instability in breast cancer.";
RL   Cancer Res. 65:10801-10809(2005).
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RX   PubMed=20019840; DOI=10.1593/neo.91084;
RA   Vesuna F., Lisok A., Kimble B., Raman V.;
RT   "Twist modulates breast cancer stem cells by transcriptional
RT   regulation of CD24 expression.";
RL   Neoplasia 11:1318-1328(2009).
//