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Cellosaurus Jurkat J77 cl20 (CVCL_DS02)

[Text version]

Cell line name Jurkat J77 cl20
Synonyms Jurkat J77cl20; J77 clone 20; J77cl20; J77.20
Accession CVCL_DS02
Resource Identification Initiative To cite this cell line use: Jurkat J77 cl20 (RRID:CVCL_DS02)
Comments Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for BAX p.Glu41Argfs*19 (c.121delG) (ClinVar=VCV000009512) (from parent cell line).
Heterozygous for BAX p.Glu41Glyfs*33 (c.121dupG) (ClinVar=VCV000009511) (from parent cell line).
Heterozygous for FBXW7 p.Arg505Cys (c.1513C>T) (ClinVar=VCV000069961) (from parent cell line).
Heterozygous for INPP5D p.Gln345Ter (c.1033C>T) (from parent cell line).
Heterozygous for INPP5D c.1097+1065_1097+1112del47 (from parent cell line).
Homozygous for MSH2 p.Arg711Ter (c.2131C>T) (ClinVar=VCV000090903) (from parent cell line).
Homozygous for MSH6 p.Phe1088Serfs*2 (c.3261delC) (ClinVar=VCV000089363) (from parent cell line).
Heterozygous for SYK p.Met34Hisfs*3 (c.98_99insG) (from parent cell line).
Heterozygous for TP53 p.Arg196Ter (c.586C>T) (ClinVar=VCV000043589) (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DS01 (Jurkat J77)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
Publications

PubMed=7759540; DOI=10.1074/jbc.270.21.12839
Niedergang F., Hemar A., Hewitt C.R., Owen M.J., Dautry-Varsat A., Alcover A.
The Staphylococcus aureus enterotoxin B superantigen induces specific T cell receptor down-regulation by increasing its internalization.
J. Biol. Chem. 270:12839-12845(1995)

Cross-references
Other Wikidata; Q54899135
Proteomic databases PRIDE; PXD001549
Entry history
Entry creation13-Jul-2016
Last entry update12-Jan-2021
Version number11