ID   Jurkat J77 cl20
AC   CVCL_DS02
SY   Jurkat J77cl20; J77 clone 20; J77cl20; J77.20
DR   PRIDE; PXD001549
DR   Wikidata; Q54899135
RX   PubMed=7759540;
CC   Sequence variation: Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11491; SYK; Simple; p.Met34Hisfs*3 (c.98_99insG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
CC   Derived from sampling site: Peripheral blood.
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_DS01 ! Jurkat J77
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 20-05-21; Version: 12
//
RX   PubMed=7759540; DOI=10.1074/jbc.270.21.12839;
RA   Niedergang F., Hemar A., Hewitt C.R., Owen M.J., Dautry-Varsat A.,
RA   Alcover A.;
RT   "The Staphylococcus aureus enterotoxin B superantigen induces specific
RT   T cell receptor down-regulation by increasing its internalization.";
RL   J. Biol. Chem. 270:12839-12845(1995).
//