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Cellosaurus MDAH041 (CVCL_E212)

[Text version]

Cell line name MDAH041
Synonyms MDAH 041; 041S
Accession CVCL_E212
Resource Identification Initiative To cite this cell line use: MDAH041 (RRID:CVCL_E212)
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_IM77 (TR9-7 )
Sex of cell Female
Age at sampling 22Y
Category Cancer cell line
Publications

PubMed=3111682
Little J.B., Nove J., Dahlberg W.K., Troilo P., Nichols W.W., Strong L.C.
Normal cytotoxic response of skin fibroblasts from patients with Li-Fraumeni familial cancer syndrome to DNA-damaging agents in vitro.
Cancer Res. 47:4229-4234(1987)

PubMed=2253239
Bischoff F.Z., Yim S.O., Pathak S., Grant G., Siciliano M.J., Giovanella B.C., Strong L.C., Tainsky M.A.
Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization.
Cancer Res. 50:7979-7984(1990)

PubMed=2000218
Bischoff F.Z., Strong L.C., Yim S.O., Pratt D.R., Siciliano M.J., Giovanella B.C., Tainsky M.A.
Tumorigenic transformation of spontaneously immortalized fibroblasts from patients with a familial cancer syndrome.
Oncogene 6:183-186(1991)

PubMed=7667317; DOI=10.1073/pnas.92.18.8493
Agarwal M.L., Agarwal A., Taylor W.R., Stark G.R.
p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.
Proc. Natl. Acad. Sci. U.S.A. 92:8493-8497(1995)

Cross-references
Encyclopedic resources Wikidata; Q54904670
Entry history
Entry creation22-Oct-2012
Last entry update12-Mar-2020
Version number8