Home  |  Contact

Cellosaurus UOXFi003-A (CVCL_EE31)

[Text version]

Cell line name UOXFi003-A
Synonyms MK088-1; GBA-PD 2#1
Accession CVCL_EE31
Resource Identification Initiative To cite this cell line use: UOXFi003-A (RRID:CVCL_EE31)
Comments From: University of Oxford; Oxford; UK.
Sequence variations Heterozygous for GBA p.Asn409Ser (c.1226A>G) (N370S) (ClinVar=VCV000004290) (EBiSC).
Disease Parkinson's disease (NCIt: C26845)
Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_WG64 ! UOXFi003-B
CVCL_EE32 ! UOXFi003-C
Sex of cell Male
Age at sampling 45-49Y
Category Induced pluripotent stem cell

PubMed=26905200; DOI=10.1016/j.stemcr.2016.01.013
Fernandes H.J.R., Hartfield E.M., Christian H.C., Emmanoulidou E., Zheng Y., Booth H., Bogetofte H., Lang C., Ryan B.J., Sardi S.P., Badger J., Vowles J., Evetts S., Tofaris G.K., Vekrellis K., Talbot K., Hu M.T., James W., Cowley S.A., Wade-Martins R.
ER stress and autophagic perturbations lead to elevated extracellular alpha-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons.
Stem Cell Reports 6:342-356(2016)

Cell line collections EBiSC; UOXFi003-A
ECACC; 66540391
Cell line databases/resources hPSCreg; UOXFi003-A
Biological sample resources BioSamples; SAMEA4454477
Other Wikidata; Q54991439
Entry history
Entry creation13-Jul-2016
Last entry update02-Jul-2020
Version number8