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Cellosaurus HPSI0514i-letw_5 (CVCL_EE95)

[Text version]
Cell line name HPSI0514i-letw_5
Synonyms WTSIi253-A
Accession CVCL_EE95
Resource Identification Initiative To cite this cell line use: HPSI0514i-letw_5 (RRID:CVCL_EE95)
Comments From: Cambridge BioResource; Cambridge; United Kingdom.
From: Wellcome Trust Sanger Institute; Hinxton; United Kingdom.
Population: Caucasian; British.
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Genome sequenced.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C1XT (WTSIi253-A-2)
Originate from same individual CVCL_EE94 ! HPSI0514i-letw_1
Sex of cell Male
Age at sampling 70-74Y
Category Induced pluripotent stem cell
Publications

PubMed=28489815; DOI=10.1038/nature22403
Kilpinen H., Goncalves A., Leha A., Afzal V., Alasoo K., Ashford S., Bala S., Bensaddek D., Casale F.P., Culley O.J., Danecek P., Faulconbridge A., Harrison P.W., Kathuria A., McCarthy D., McCarthy S.A., Meleckyte R., Memari Y., Moens N., Soares F., Mann A., Streeter I., Agu C.A., Alderton A., Nelson R., Harper S., Patel M.J., White A., Patel S.R., Clarke L., Halai R., Kirton C.M., Kolb-Kokocinski A., Beales P., Birney E., Danovi D., Lamond A.I., Ouwehand W.H., Vallier L., Watt F.M., Durbin R., Stegle O., Gaffney D.J.
Common genetic variation drives molecular heterogeneity in human iPSCs.
Nature 546:370-375(2017)

PubMed=35933957; DOI=10.1016/j.scr.2022.102880
Liu J.-S., Black G.C., Kimber S.J., Sergouniotis P.I.
Generation of a human induced pluripotent stem cell line carrying the TYR c.575C>A (p.Ser192Tyr) and c.1205G>A (p.Arg402Gln) variants in homozygous state using CRISPR-Cas9 genome editing.
Stem Cell Res. 64:102880-102880(2022)

Cross-references
Cell line collections (Providers) ECACC; 77650396
Cell line databases/resources HipSci; HPSI0514i-letw_5
hPSCreg; WTSIi253-A
Biological sample resources BioSamples; SAMEA3967410
Encyclopedic resources Wikidata; Q54890905
Gene expression databases ArrayExpress; E-MTAB-4057
Entry history
Entry creation13-Jul-2016
Last entry update29-Jun-2023
Version number14