ID   FaDu/T
AC   CVCL_EG58
SY   FaDu/T-200
DR   cancercelllines; CVCL_EG58
DR   Wikidata; Q54833223
RX   PubMed=21833476;
CC   Population: Indian.
CC   Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; c.151-1G>T; ClinVar=VCV000422058; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 3595; FAT1; Simple; p.Lys3277Asnfs*4 (c.9828delG) (p.Gly3276fs); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Leu (c.743G>T); ClinVar=VCV000230253; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.
DI   NCIt; C4043; Hypopharyngeal squamous cell carcinoma
DI   ORDO; Orphanet_494547; Squamous cell carcinoma of the hypopharynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1218 ! FaDu
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 05-10-23; Version: 14
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RX   PubMed=21833476; DOI=10.3892/or.2011.1418;
RA   Ma J.-K., Lu S.-M., Yu L., Tian J.-J., Li J.-F., Wang H.-B., Xu W.;
RT   "FaDu cell characteristics induced by multidrug resistance.";
RL   Oncol. Rep. 26:1189-1195(2011).
//