| Cell line name | Hep-G2 SimpleCell O-GalNAc KI GalNAc-T3 |
|---|---|
| Synonyms | HepG2SC+T3 |
| Accession | CVCL_EI11 |
| Resource Identification Initiative | To cite this cell line use: Hep-G2 SimpleCell O-GalNAc KI GalNAc-T3 (RRID:CVCL_EI11) |
| Comments | Population: Caucasian. Characteristics: Cell engineered to produce only truncated GalNAc or NeuAc-alpha-2-6-GalNAc O-glycans. Knockout cell: Method=ZFN; HGNC; 24338; C1GALT1C1. Transfected with: HGNC; 24137; B4GALNT3. Derived from sampling site: Liver. |
| Sequence variations | Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). |
| Disease | Hepatoblastoma (NCIt: C3728) Hepatoblastoma (ORDO: Orphanet_449) |
| Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
| Hierarchy | Parent: CVCL_S027 (Hep-G2 SimpleCell O-GalNAc) |
| Sex of cell | Male |
| Age at sampling | 15Y |
| Category | Cancer cell line |
| Publications | PubMed=26566661; DOI=10.15252/embr.201540796 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54882783 |
| Proteomic databases | PRIDE; PXD002770 |
| Entry history | |
| Entry creation | 13-Jul-2016 |
| Last entry update | 20-May-2021 |
| Version number | 12 |