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Cellosaurus ER-Fadu (CVCL_EI27)

Cell line name ER-Fadu
Accession CVCL_EI27
Resource Identification Initiative To cite this cell line use: ER-Fadu (RRID:CVCL_EI27)
Comments Selected for resistance to: ChEBI; CHEBI:114785; Erlotinib.
Omics: Transcriptome analysis.
Sequence variations Homozygous for CDKN2A c.151-1G>T; splice donor mutation (from parent cell line).
Heterozygous for TP53 p.Arg248Leu (c.743G>T) and c.376-1G>A (from parent cell line).
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1218 (FaDu)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=25888065; DOI=10.1016/j.molonc.2015.03.008
Stanam A., Love-Homan L., Joseph T.S., Espinosa-Cotton M., Simons A.L.
Upregulated interleukin-6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma.
Mol. Oncol. 9:1371-1383(2015)

Cross-references
Gene expression databases GEO; GSM1524313
GEO; GSM1524314
GEO; GSM1524315
Other Wikidata; Q54832418